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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERO1L All Species: 24.24
Human Site: S143 Identified Species: 33.33
UniProt: Q96HE7 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96HE7 NP_055399.1 468 54393 S143 R L G A V D E S L S E E T Q K
Chimpanzee Pan troglodytes XP_509950 468 54427 S143 R L G A V D E S L S E E T Q K
Rhesus Macaque Macaca mulatta XP_001103965 468 54383 S143 R L G A V D E S L S E E T Q K
Dog Lupus familis XP_547813 468 54343 S143 R L G A V D E S L S E E T Q K
Cat Felis silvestris
Mouse Mus musculus Q8R180 464 54066 V139 Q A E R L G A V D E S L S E E
Rat Rattus norvegicus Q8R4A1 464 54000 V139 Q A E R L G A V D E S L S E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515503 465 53870 S140 R L G A V D E S L S E E T Q R
Chicken Gallus gallus XP_421473 463 52908 V138 E A N R L G A V D E S L S K E
Frog Xenopus laevis Q6DD71 465 53720 S141 R L S A V D E S L S V E T Q E
Zebra Danio Brachydanio rerio Q7T3D1 489 56571 G134 E K L G A V N G S L S D E T R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A6 483 55641 F153 A C S D G E D F D S S L G F L
Honey Bee Apis mellifera XP_623933 471 55049 L145 R A Q Y D D C L Y S A K D H N
Nematode Worm Caenorhab. elegans Q7YTU4 478 55136 D138 A D A G N N I D P M D R T L H
Sea Urchin Strong. purpuratus XP_796844 897 101920 L569 T E E D E D Q L G A L D T T I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7S7 469 53812 T163 P Q G A V D R T I D N R A F R
Baker's Yeast Sacchar. cerevisiae Q03103 563 65014 C143 A D D S D D E C K F L D Q L C
Red Bread Mold Neurospora crassa Q7SEY9 668 75589 L142 K R P L Q G K L G E D V G E S
Conservation
Percent
Protein Identity: 100 99.5 98.7 96.3 N.A. 91.8 91.4 N.A. 84.6 77.7 70.9 62.1 N.A. 46.1 48.4 41.4 29.3
Protein Similarity: 100 99.5 99.3 97.8 N.A. 95.9 95.7 N.A. 90.1 85.4 83.9 75.4 N.A. 64.1 65.6 60.8 37.6
P-Site Identity: 100 100 100 100 N.A. 0 0 N.A. 93.3 0 80 0 N.A. 6.6 20 6.6 13.3
P-Site Similarity: 100 100 100 100 N.A. 33.3 33.3 N.A. 100 26.6 86.6 13.3 N.A. 20 26.6 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. 37.9 22.5 22.1
Protein Similarity: N.A. N.A. N.A. 55.6 41.2 38
P-Site Identity: N.A. N.A. N.A. 26.6 13.3 0
P-Site Similarity: N.A. N.A. N.A. 46.6 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 18 24 6 42 6 0 18 0 0 6 6 0 6 0 0 % A
% Cys: 0 6 0 0 0 0 6 6 0 0 0 0 0 0 6 % C
% Asp: 0 12 6 12 12 59 6 6 24 6 12 18 6 0 0 % D
% Glu: 12 6 18 0 6 6 42 0 0 24 30 36 6 18 24 % E
% Phe: 0 0 0 0 0 0 0 6 0 6 0 0 0 12 0 % F
% Gly: 0 0 36 12 6 24 0 6 12 0 0 0 12 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 6 % H
% Ile: 0 0 0 0 0 0 6 0 6 0 0 0 0 0 6 % I
% Lys: 6 6 0 0 0 0 6 0 6 0 0 6 0 6 24 % K
% Leu: 0 36 6 6 18 0 0 18 36 6 12 24 0 12 6 % L
% Met: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % M
% Asn: 0 0 6 0 6 6 6 0 0 0 6 0 0 0 6 % N
% Pro: 6 0 6 0 0 0 0 0 6 0 0 0 0 0 0 % P
% Gln: 12 6 6 0 6 0 6 0 0 0 0 0 6 36 0 % Q
% Arg: 42 6 0 18 0 0 6 0 0 0 0 12 0 0 18 % R
% Ser: 0 0 12 6 0 0 0 36 6 48 30 0 18 0 6 % S
% Thr: 6 0 0 0 0 0 0 6 0 0 0 0 48 12 0 % T
% Val: 0 0 0 0 42 6 0 18 0 0 6 6 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 0 0 6 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _